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    The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia

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    Authors
    Vordermeier, M.
    Ameni, G.
    Berg, S.
    Bishop, Richard P.
    Robertson, B.D.
    Aseffa, A.
    Hewinson, R.G.
    Young, D.B.
    Date
    2012-05
    Language
    en
    Type
    Journal Article
    Accessibility
    Limited Access
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    Citation
    Vordermeier, M., Ameni, G., Berg, S., Bishop, R., Robertson, B.D., Aseffa, A., Hewinson, R.G. and Young, D.B. 2012. The influence of cattle breed on susceptibility to bovine tuberculosis in Ethiopia. Comparative Immunology, Microbiology and Infectious Diseases 35(3): 227-232.
    Permanent link to cite or share this item: http://hdl.handle.net/10568/16437
    DOI: https://dx.doi.org/10.1016/j.cimid.2012.01.003
    Abstract/Description
    Bovine tuberculosis in domestic livestock such as cattle is an economically important disease with zoonotic potential, particularly in countries with emerging economies. We discuss the findings of recent epidemiological and immunological studies conducted in Ethiopia on host susceptibility differences between native zebu and the exotic Holstein–Friesian cattle that are increasingly part of the Ethiopian National herd, due to the drive to increase milk yields. These findings support the hypothesis that native Zebu cattle are more resistant to bovine tuberculosis. We also summarise the results of experimental infections that support the epidemiological data, and of laboratory experiments that suggest a role for the innate immune response, and in particular interleukin-6, in the outcome of bovine tuberculosis infection.
    CGIAR Affiliations
    Agriculture for Nutrition and Health
    AGROVOC Keywords
    TUBERCULOSIS; ANIMAL DISEASES; CATTLE
    Subjects
    ANIMAL DISEASES; ANIMAL HEALTH; BREEDS; CATTLE; GENETICS; LIVESTOCK;
    Countries
    ETHIOPIA
    Regions
    AFRICA; EAST AFRICA
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