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dc.contributor.authorPain, A.
dc.contributor.authorRenauld, H.
dc.contributor.authorBerriman, M.
dc.contributor.authorMurphy, L.
dc.contributor.authorYeats, C.A.
dc.contributor.authorWeir, W.
dc.contributor.authorKerhornou, A.
dc.contributor.authorAslett, M.
dc.contributor.authorBishop, Richard P.
dc.contributor.authorBouchier, C.
dc.contributor.authorBouchier, C.
dc.contributor.authorCochet, M.
dc.contributor.authorCoulson, R.M.R.
dc.contributor.authorCronin, A.
dc.contributor.authorVilliers, Etienne P. de
dc.contributor.authorFraser, A.
dc.contributor.authorFosker, N.
dc.contributor.authorGardner, M.
dc.contributor.authorGoble, A.
dc.contributor.authorGriffiths-Jones, S.
dc.contributor.authorHarris, D.E.
dc.contributor.authorKatzer, F.
dc.contributor.authorLarke, N.
dc.contributor.authorLord, A.
dc.contributor.authorMaser, P.
dc.contributor.authorMcKellar, S.
dc.contributor.authorMooney, P.
dc.contributor.authorMorton, F.
dc.contributor.authorNene, Vishvanath
dc.contributor.authorO'Neil, S.
dc.contributor.authorPrice, C.
dc.contributor.authorQuail, M.A.
dc.contributor.authorRabbinowitsch, E.
dc.contributor.authorRawlings, N.D.
dc.contributor.authorRutter, S.
dc.contributor.authorSaunders, D.
dc.contributor.authorSeeger, K.
dc.contributor.authorShah, Tushaar
dc.contributor.authorSquares, R.
dc.contributor.authorSquares, S.
dc.contributor.authorTivey, A.
dc.contributor.authorWalker, A.R.
dc.contributor.authorWoodward, J.
dc.contributor.authorDobbelaere, D.A.E.
dc.contributor.authorLangsley, G.
dc.contributor.authorRajandream, M.A.
dc.contributor.authorMcKeever, Declan J.
dc.contributor.authorShiels, B.
dc.contributor.authorTait, A.
dc.contributor.authorBarrell, B.
dc.contributor.authorHall, N.
dc.date.accessioned2013-07-03T05:26:09Z
dc.date.available2013-07-03T05:26:09Z
dc.date.issued2005
dc.identifier.citationScience;309(5731): 131-133
dc.identifier.issn0036-8075
dc.identifier.urihttp://hdl.handle.net/10568/33166
dc.description.abstractTheileria annulata and T. parva are closely related protozoan parasites that cause lymphoproliferative diseases of cattle. We sequenced the genome of T. annulata and compared it with that of T. parva to understand the mechanisms underlying transformation and tropism. Despite high conservation of gene sequences and synteny, the analysis reveals unequally expanded gene families and species-specific genes. We also identify divergent families of putative secreted polypeptides that may reduce immune recognition, candidate regulators of host-cell transformation, and a Theileria-specific protein domain [frequently associated in Theileria (FAINT)] present in a large number of secreted proteins.
dc.language.isoen
dc.sourceScience
dc.subjectTHEILERIA ANNULATA
dc.subjectTHEILERIA PARVA
dc.subjectGENOME
dc.subjectHOSTS
dc.subjectCELL
dc.titleGenome of the host-cell transforming parasite Theileria annulata compared with T. parva
dc.typeJournal Article
cg.subject.ilriANIMAL DISEASES
cg.subject.ilriLIVESTOCK
cg.identifier.statusOpen Access
cg.identifier.doihttps://dx.doi.org/10.1126/science.1110418


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